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    “This is a serious game changer”: Merck’s antivirals reduce the risk of COVID-19 hospitalization and death by half, data show

    Merck said on Friday that COVID-19 antivirals could be a powerful tool to reduce the risk of hospitalization or death by about half in late-stage trials and reduce pandemics, as well as investors and healthcare professionals. I cheered.

    Pharmaceutical company
    MRK,
    + 9.56%

    Molnupiravir, an oral antiviral drug developed in collaboration with partner Ridgeback Biotherapeutics, risks hospitalization or death in adult patients at risk of mild to moderate COVID in an interim analysis of late study data. Said that it was reduced by about 50%.

    Merck stock 9% surge on early Friday trading Investors welcomed COVID’s long-awaited treatment. Although several effective vaccines have been developed for this disease, far fewer treatments have emerged, requiring infusions and some treatments that must be given in the clinical setting.

    Molnupiravir is a tablet that is orally administered in the form of capsules every 12 hours for 5 days. According to Clinicaltrials.gov.

    reference: That’s why COVID-19 Booster Shot is good for your business

    By day 29 of the Phase 3 trial, patients receiving molnupiravir did not die compared to the eight patients who died from placebo. The company is currently planning to file an emergency use authorization application for treatment from the Food and Drug Administration and seek approval from other regulatory agencies around the world.

    Merck plans to offer 10 million courses of treatment by the end of the year. The US government has already promised to buy about 1.7 million courses of medicine after getting the EUA.

    The company said the results were so good that it stopped the study early in consultation with an independent data monitoring committee and the FDA.

    Health experts praised the news, saying it would make a big difference in the fight against coronavirus-borne disease, which has killed about 5 million people since the outbreak.

    The news comes from the fact that the United States records an average of just under 2,000 COVID deaths per day. According to the New York Times tracker I improved the recent trend a little. Hospitalizations and new cases are on the decline, but the daily mortality rate for the past few weeks has exceeded 2,000.

    Alaska remains the state with the newest cases measured on a per capita basis, and its hospital system remains under severe stress. Elsewhere, there are signs of improvement in some of the states that were recent hotspots. In Florida, it is currently reported to be less than 6,000 per day, from an average of over 20,000 per day for most of August.

    In Florida, 55,009 inhabitants have died from the virus, with a total of 3.57 million confirmed cases. According to the 2020 census, the state’s population is just over 21.5 million.

    reference: The biggest risk investors face during this earnings season lies under the hood.

    NS Centers for Disease Control and Prevention Vaccine Tracker Shows that 184.6 million people living in the United States are fully vaccinated. This represents about 55.6% of the population, and this number has remained relatively unchanged for several weeks.

    Physicians are increasingly turning to monoclonal antibody drugs to treat high-risk patients who become ill with Covid-19. The WSJ investigates how treatments work and why they are important for saving lives. Illustration: Jacob Reynolds / WSJ

    Widely welcomed as a hero in 2020, the hospital staff, with nightly applause from windows and balconies, are hostile to patients who are increasingly angry with safety rules aimed at stopping the spread of the virus. We are exposed to threats and violence. The Associated Press reported.

    “A year ago, we were healthcare heroes and everyone was applauding for us,” said Dr. Stu Coffman, a doctor in the Dallas-based emergency room. “And now we’re in some areas where we’re harassed, unbelievable, and ridiculed for what we’re trying to do. It’s just depressing and frustrating. . “

    Cox Medical Center Branson, Missouri, said it began giving panic buttons to up to 400 nurses and other employees after triple annual assaults reached 123 between 2019 and 2020. Said. The AP reported that one nurse had to take an x-ray of the shoulder after the attack.

    Coronavirus latest information: BioNTech co-founders say COVID-19 will be manageable, but may last for years.

    Elsewhere, Russia recorded a record daily death toll at 887 for the fourth consecutive year. The Moscow Times reported. This brings Russia’s official coronavirus death to 208,142, the highest in Europe.

    Australia plans to lift some international travel restrictions in November. BBC News reported. Australia’s decision to completely close its borders caused controversy because it left many citizens abroad, but it also succeeded in curbing its spread. Australia has recorded less than 1,000 deaths in a pandemic.

    Finland will begin vaccination of fur farm mink against COVID with an experimental vaccine. Reported by NDTV.com. Mink is known to be susceptible to disease and transmitted to humans.Last year Denmark Weeded out the entire mink population As a precautionary measure.

    The World Health Organization said that only 2% of the half population of African countries is vaccinated against COVID. AFP reported. Fifteen of the 54 countries on the continent have vaccinated at least 10% of people, achieving the WHO’s May 30 global target.

    reference: Three prominent doctors on the best use of rapid home COVID tests — and which single test has been “shown to be very accurate”

    The flu season is approaching, and health experts expect it to be worse than last year. The WSJ’s Felicia Schwartz explains why this could be an earlier and tougher season, and the precautions people can take during the Covid-19 pandemic.Photo: Joe Raidle / Getty Images

    Latest tabulation

    Globally, the total number of coronavirus-borne diseases exceeded 233.8 million on Friday, with deaths exceeding 4.78 million. Data aggregated by Johns Hopkins University..

    The United States continues to lead the world with a total of 43.4 million cases and 697,870 deaths.

    India has 33.8 million people after the United States, with 448,339 deaths. Brazil has the second highest number of deaths, with 596,749 and 21.4 million.

    In Europe, Russia reports the highest death toll at 204,424, followed by the United Kingdom at 137,043.

    China, The virus was first discovered in late 2019, According to official numbers, there are 108,454 confirmed cases and 4,809 deaths, which are widely believed to be significantly underreported.

    “This is a serious game changer”: Merck’s antivirals reduce the risk of COVID-19 hospitalization and death by half, data show

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