New research published in Diabetes mellitus (Journal of the European Diabetes Society) has found that poor post-sleep daily activities and poor sleep quality are associated with elevated postprandial glycemic levels and poor glycemic control.
The study was conducted by Neli Tsereteli of the Lund University Diabetes Center in Malme, Sweden, and Paul Franks of the Lund University Diabetes Center in Malmo, Sweden and Harvard Chan School of Public Health in Boston, Massachusetts, USA.
The authors have nighttime fluctuations time of sleeping, Efficiency, or timing affects the postprandial (postprandial) glucose response to the next day’s breakfast.
Eating, exercising and sleeping are the basic elements of a healthy lifestyle. However, the role of sleep, which generally affects the control of blood glucose levels in healthy people, has so far been the subject of relatively few studies.Sleep disorders often occur with others Health problems, It allows them to act as a general measure of health.
Sleep quality is also directly related to many life-threatening conditions such as cardiovascular disease, obesity, and type 2 diabetes (T2D). Sleep disorders caused by conditions such as obstructive sleep apnea are associated with both the prevalence of type 2 diabetes and the risk of complications resulting from the disease. This and other evidence suggests a strong link between both sleep quality and duration and the body’s ability to regulate properly. Blood glucose level..
The author states: “Although there are many large prospective cohort studies focusing on the relationship between self-reported sleep, illness, and health, objective data on sleep and postprandial glucose metabolism are usually identified as a tightly controlled environment. A subgroup suffering from sleep disorders due to pregnancy, sleep aspiration, depression, obesity, diabetes, etc …. Therefore, the effect of sleep on glucose metabolism in healthy people. I need more evidence of. “
In the following research groups, researchers found that sleep (duration, efficiency, and midpoint between bedtime and wake-up) and postprandial blood glucose response (changes in postprandial blood glucose levels) for breakfast with various major nutrient compositions. I investigated the relationship. 953 healthy adults from the United Kingdom and the United States. Participants were enrolled in ZOE Personalized REsponses to DIetary Composition Trial 1 (PREDICT1), the world’s largest scientific nutrition research. This was carried out over a 14-day period and included consuming a standardized test diet containing a known content of carbohydrates and fats. , Protein, and dietary fiber. Blood glucose levels are monitored using a continuous glucose monitoring (CGM) device that takes sample data every 15 minutes throughout the study, and sleep monitoring is a wrist-worn device that measures participants’ movements. Performed by the actigraph unit.
In this study, there was no statistically significant association between length of sleep and postprandial glycemic response, but there was a significant interaction when considering the nutritional content of the breakfast diet. understood. Longer sleep periods are associated with lower post-breakfast blood glucose levels of high carbohydrates and fats, indicating better control of blood glucose levels. In addition, researchers observed an internal effect that if study participants slept longer than usual, they were more likely to have lower postprandial blood glucose levels after breakfast with high carbohydrates or high fats the next day.
The authors also found a significant association between sleep efficiency (the ratio of sleep time to total length), which indicates sleep disorders, and glycemic control, which is independent of the nutritional composition of the next day’s breakfast. On average, participants with high sleep efficiency were more likely to have lower postprandial blood glucose levels than participants with low sleep efficiency. As participants slept more efficiently than usual, postprandial blood glucose levels also tended to be lower than normal.
Sleep timing has an important effect, and blood sugar levels rise when the midpoint of sleep is delayed. This effect is primarily caused by changes in sleep onset (later falling asleep) rather than differences in sleep offsets (later awakening), both when compared between study participants and when looking at changes in sleep. Patterns of individual participants observed to adversely affect glycemic control in.
The author states: “Our data suggest that sleep time, efficiency, and midpoint are important determinants of postprandial blood glucose control at the population level, but to optimize sleep recommendations, use these. It shows that it needs to be tailored to the individual … These findings emphasize the importance of sleep’s role in regulating metabolic health, and patients minimize the risk of metabolic disease. You may need a combination of both general and more personalized sleep guidelines to be able to limit yourself. “
They conclude that: “The results of this study may help with lifestyle strategies to improve after-meal. blood glucose Focus on levels, early bedtime routines and maximize high quality uninterrupted sleep.A combination of both generalized and more personalized sleep guidelines may be needed to ensure optimal metabolic health. As such Maximize the effectiveness of guidelines for diabetes prevention. ”
Neli Tsereteli et al, Effect of sleep deprivation on dysregulated glycemic control under standardized dietary conditions, Diabetes mellitus (2021). DOI: 10.1007 / s00125-021-05608-y
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