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    In 1st, US surgeons transplant pig heart into human patient

    Carla K. Johnson

    This photo, provided by the University of Maryland School of Medicine, shows a pig heart for transplantation into a Baltimore patient David Bennett by a member of the surgical team on Friday, January 7, 2022. The hospital said on Monday, January 10, 2022. He said he was doing well three days after a very experimental surgery. Credits: Mark Teske / University of Maryland School of Medicine via AP

    In the first stages of medical care, doctors transplanted a pig’s heart into a patient in the last effort to save his life, and Maryland Hospital successfully on Monday three days after his highly experimental surgery. I said I’m doing it.

    It’s too early to know if surgery will actually work, but it represents a step in decades of quest to someday use animal organs for life-saving transplants.By transplantation, according to doctors at the University of Maryland Medical Center heart From genetically modified animals human body Without refusing immediately.

    Patient David Bennett, 57, knew there was no guarantee that the experiment would work, but he was dying, ineligible for a human heart transplant, and had no other choice, his son said in the Associated Press. Told to.

    According to a statement from the University of Maryland School, Bennett said the day before the surgery, “I was either dying or doing this transplant. I want to live. I know it’s a shot in the dark, but that’s me. It’s the last choice. ” Of medicine.

    There is a huge shortage of human organs donated for transplants, and scientists are instead trying to understand how to use animal organs. Last year, there were just over 3,800 heart transplants in the United States, a record number, according to the United Network for Organ Sharing, which oversees the US transplant system.

    First, US surgeons transplant pig hearts into human patients

    In this photo, provided by the University of Maryland School of Medicine, a member of the surgical team is performing a pig heart transplant to a Baltimore patient David Bennett on Friday, January 7, 2022. On Monday, January 10, 2022, he said he was doing well three days after the hospital’s very experimental surgery. Credits: Mark Teske / University of Maryland School of Medicine via AP

    “If this goes well, there will be an infinite supply of these organs for suffering patients,” said Dr. Muhammad Mohiudin, director of science for the university’s animal-to-human transplant program.

    However, previous attempts at such transplants, or xenografts, have failed. This is mainly due to the rapid rejection of animal organs by the patient’s body. In particular, in 1984, Baby Fae, a dying baby, lived for 21 days with a baboon heart.

    This difference: Maryland surgeons used a genetically-edited pig’s heart to remove the sugar that causes ultrafast organ rejection in its cells.

    “I think we can characterize it as a watershed event,” said Dr. David Klassen, Chief Medical Officer at UNOS, about the Maryland transplant.

    Still, Klassen warned that this is only the first tentative step in investigating whether xenotransplantation will ultimately work.

    First, US surgeons transplant pig hearts into human patients

    This family-provided photo is from left to right: David Bennett Jr., Preston Bennett, David Bennett Sr., Gillian Bennett, Nicole (Bennett) McCray, Sawyer Bennett, Kristi Bennett. In his last effort to save his life, Bennett Sr. told the hospital on Monday, January 10, 2022 that he was doing well three days after highly experimental surgery. Credit: Byron Dillard via AP

    The Food and Drug Administration, which oversees xenotransplantation experiments, has allowed surgery under so-called “compassionate use” emergency permits, which can be used when life-threatening patients have no other option.

    Just last September, researchers in New York conducted an experiment suggesting that these types of pigs may be promising for animal-to-human transplantation. Doctors temporarily attached the pig’s kidneys to the deceased human body and observed it begin to function.

    The Maryland transplant takes their experiment to the next level, said Dr. Robert Montgomery, who led the experiment at NYU Langone Health.

    “This is a truly amazing advance,” he said in a statement. “As a heart transplant recipient myself suffering from hereditary heart disease, I am excited about this news and this news gives to my family and other patients and is ultimately saved by this breakthrough. I hope that. “

    • First, US surgeons transplant pig hearts into human patients

      In this photo, provided by the University of Maryland School of Medicine, Dr. Bartley Griffith will take a selfie with patient David Bennett in Baltimore in January 2022. Saving his life, the hospital said on Monday, January 10, 2022, three days after highly experimental surgery, he was on track. Credit: Dr. Bartley Griffith / University of Maryland School of Medicine via AP

    • First, US surgeons transplant pig hearts into human patients

      From left to right, this family-provided photo shows David Bennett Jr., David Bennett Sr., and Nicole (Bennett) McCray at the 2014 Carnival. -Abandoning his life-saving efforts, the hospital said on Monday, January 10, 2022, three days after highly experimental surgery, he was doing well. Credit: David Bennett Jr via AP.Offer

    It will be important to share the data that will be collected Transplant Before opening up options to more patients, Hastings Center researcher Karen Mashke said in ethics Policy recommendations For the first clinical trial under a grant from the National Institutes of Health.

    “It is not advisable to rush into an animal-to-human transplant without this information,” Maschke said.

    The surgery last Friday took 7 hours at Baltimore Hospital.

    “He understands the magnitude of what has been done and really understands the importance of it,” David Bennett Jr. said of his father. “He couldn’t live, or he could last a day, or he could last a couple of days, that is, we are in an unknown state at this point.”


    Pig-to-human transplantation is one step closer with new tests


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    Quote: First, a US surgeon transplanted a pig heart into a human patient (January 10, 2022) and January 10, 2022 https://medicalxpress.com/news/2022-01-1st Obtained from -surgeons-transplant-pig-heart.html.

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    In 1st, US surgeons transplant pig heart into human patient Source link In 1st, US surgeons transplant pig heart into human patient

    The post In 1st, US surgeons transplant pig heart into human patient appeared first on California News Times.

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