Oxford University has begun recruiting Phase I trials to test the Ebola vaccine in human volunteers. The first vaccination has already taken place.
All planned samples of 26 participants who must be evaluated as healthy and 18-55 years old will receive a single dose of ChAdOx1biEBOV vaccine at the university. After vaccination, participants will be monitored through several visits over a 6-month period, with results expected in the second quarter of 2022.
Vaccine is based on ChAdOx1 virus, A weakened version of the common cold virus (adenovirus), which is genetically modified and cannot be replicated in humans. This vector was previously successfully used in the ChAdOx1 nCoV-19 vaccine, or the Oxford-AstraZeneca vaccine.
Professor Teresa Lambe, an associate professor at the Jenner Institute and a principal scientific researcher at Oxford University, said:
“Sporadic Ebola virus outbreaks are still occurring in affected countries, endangering the lives of individuals, especially front-line healthcare workers. More to tackle this catastrophic disease. I need a lot of vaccines. “
Dr. Daniel Jenkin, Principal Researcher at the Jenner Institute at Oxford University, said: “Recent advances have approved a vaccine against one of the viruses responsible for Ebola disease. Several different species of virus and each of these require a targeted immune response to provide protection. May do.
“We have designed a new vaccine that targets the two viruses that caused the outbreak and death of almost all Ebola viruses. We are currently looking forward to testing this in Phase I clinical trials. trial.. “
Dr. Paola Chicconi, Principal Investigator for the Exam at the Jenner Institute at Oxford University, said: COVID-19 Vaccine) demonstrates that vaccines can be produced quickly, in large quantities, at low cost, in easy-to-use storage conditions in developing countries.
“This study provides valuable data on the safety and immunological aspects of the new polyvalent Ebola virus ChAdOx1 vaccine.”
Volunteers interested in registering for a study can register online.
Further testing of the vaccine is expected to begin in Tanzania by the end of 2021.
Quote: Ebola vaccine to start human trials (November 11, 2021) from https: //medicalxpress.com/news/2021-11-ebola-vaccine-human-trials.html November 11, 2021 Obtained on the day
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