Friday, September 17, 2021

Diet and weight loss to achieve type 2 diabetes remission should be goal for GPs

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Achieving “relief” in patients with type 2 diabetes through diet and weight loss should be a major therapeutic goal for GPs and healthcare professionals, and a large scale of clinical evidence led by researchers at UCL and Aston University. The review is closed.

Type 2 Diabetes mellitus (T2DM) is a serious condition that occurs when the body resists insulin produced by the pancreas and does not produce enough insulin. It leads to high levels of sugar (glucose) in the blood and is associated with multiple health problems, including increased risk of heart disease, blindness, and amputation. In the UK, T2DM affects about 3.9 million people and 179 million people worldwide. The care and treatment of T2DM costs the NHS approximately £ 10 billion annually.

The corresponding author, Dr. Duane Mellor of Aston University, said: Relief It should be discussed as a primary therapeutic goal with people with type 2 diabetes. Although there are multiple dietary approaches that have been shown to result in T2DM remission, dietary alternatives now provide the highest quality evidence. Low-carb diets have been shown to be very effective and should also be considered as a diet for remission. “

The lead author, Dr. Adrian Brown of UCL School of Medicine, said:Shows significant loss weightThrough either weight loss surgery or diet, 10-15 kg can result in remission of type 2 diabetes (non-diabetic blood sugar levels). “

For research Journal of Human Nutrition & Dietetics, Professional dietitians and obesity specialists have conducted a critical narrative review of more than 90 research papers covering international clinical trials and clinical practice data on diets used to treat type 2 diabetes.

In this study, while dietary alternatives helped about 1 in 3 (36%) people achieve remission, Low carb diet One in five (17.6%) was able to help achieve and maintain remission for at least two years. Those who lost the most weight and lost weight using both of these diets were able to maintain remission.

Calorie restriction and a Mediterranean diet could also help people achieve remission, but at a much lower rate. Only about 5% of people on a calorie-restricted diet maintained remission after one year, while only 15% of people on a Mediterranean diet maintained remission after one year.

In reaching their findings, the research team had to explain the fact that there was no single definition of remission. This is usually defined as returning to non-diabetic blood glucose levels (glycated hemoglobin

In addition, some reports suggest that low-carb diets can normalize blood sugar levels without weight loss. This happens when carbohydrates are broken down into sugars when eaten and blood sugar levels rise. A low-carb diet means less blood sugar appears in the bloodstream, leading to better blood sugar control. However, if weight loss is not achieved, but individuals can achieve non-diabetic blood glucose levels, the authors suggest that the underlying mechanism of T2DM has not been addressed and should instead be called palliative.

Dr. Brown said: “The main driving force for remission remains the degree of weight loss a person has achieved, thus suggesting that this is not remission for those who have not achieved weight loss but have achieved non-diabetic blood glucose levels. It’s not itself, but rather the “alleviation” of their diabetes. “

Research Weight loss It appears to be the best predictor of successful remission and assumes a loss of fat from the pancreas and liver. They can compare how these diets work in different ethnic groups, as T2DM can occur in underweight in different ethnic groups that may lose less weight. It states that it is important for future research.

Dr. Meller added: “Not everyone can achieve remission, but young (under 50) men with type 2 diabetes and who are losing weight are more likely to succeed.

“This may be because these people can deal with the causes of diabetes. Therefore, the ability of the pancreas to produce insulin and the liver’s ability to use insulin is restored, but this is improved by others. That doesn’t mean they won’t succeed. They lose their diet, lifestyle and weight.

“Whether a person achieves remission, diminishes blood Sugar content is important in controlling the adverse effects of type 2 diabetes and reducing the risk of complications. But when choosing a diet, the most important thing is to choose the one that suits you. In other words, choose one that is likely to stick to you in the long run. “

The first conference that led to the writing of this treatise was supported by the British Dietitians Association and the British Diabetes Society.


International standards for remission of type 2 diabetes have been established


For more information:
Adrian Brown et al., Diet Strategy for Relief of Type 2 Diabetes: Story Review, Journal of Human Nutrition and Dietetics (2021). DOI: 10.1111 / jhn.12938

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Aston University

Quote: Diet and Weight Loss to Achieve Type 2 Diabetes Relief Obtained from https://medicalxpress.com/news/2021-09-diet-weight-loss-diabetes-remission on September 2, 2021 Must be the goal of the GP (2021, September 2nd) .html

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