Breast milk from Mennonite moms on farms may better protect babies from allergies

Date:

Credit: Pinterest / CC0 public domain

Atopic diseases such as eczema, allergic rhinitis, asthma, and food allergies are closely associated with airborne particles such as pollen, dust, mold, and animal scales, or allergies to foods such as peanuts, milk, soybeans, shellfish, and wheat. It is related. .. Until the early 20th century, allergies were considered a rare illness. However, from the 1920s to the 1930s, especially after the second half of the 20th century, the epidemic of allergies increased explosively in Western society. For example, the European Academy of Allergy and Clinical Immunology estimates that half of the EU’s population will be allergic by 2025. It has increased by 20 percentage points since 2015. Similarly, a survey from 2020 estimates it to be around 100 million (30%). Today, Americans of all ages have allergies.

What is the driving force behind this ongoing explosion?With multiple lifestyles Environmental risk factors It has been proposed. These include increased use of broad-spectrum antibiotics, detergents, antiseptic soaps, caesarean sections, and home changes such as reduced ventilation, increased carpet and furniture, and increased temperatures. Another possible factor is that children steadily reduce their playing time outdoors, resulting in less physical activity, higher obesity index, shallower breathing patterns, less exposure to bacteria, and less exposure to bacteria. Increased exposure to indoor allergens.

Traditional agricultural lifestyle may be a protecting factor

“Studies on very traditional farmers in Europe and North America point to another lifestyle risk factor: reduced consumption of non-pasteurized farms. milk, Exposure to livestock and stables associated with transport by large families, horses and buggies, “said Dr. Kirsi Järvinen-Seppo, associate professor of the Department of Pediatric Allergy and Immunology and the Center for Food Allergies, University of Rochester. ..

“Such a lifestyle was once common around the world, but today it is largely restricted in Western countries. Religious community, Amish and Mennonites of the Old Order. Allergies are much less common among them, suggesting that their traditional lifestyle may be a protective factor for the development of atopic dermatitis. “

In the study published today Immunology Frontier, Järvinen-Seppo et al. Have found evidence that this “farm life effect” that prevents the development of allergies is partially inherited from mothers to babies. Breast milk..

“Here, the milk of mothers in the old-order menonite community contains high levels of high levels of IgA antibodies against food allergens, dustmite, and livestock-related bacteria, as well as certain cytokines, which are important signaling proteins for regulation. “Immunosystem,” says Dr. Julie Takar, an associate professor of microbiology and immunology and biostatistics at the University of Rochester, and co-author of the study.

“Our study was the first to compare the amounts of antibodies, cytokines, milk oligosaccharides, metabolites, and important microbial flora in breast milk between women in a very traditional community and women in nearby cities. Our results show women on such traditional farms that they produce immunity through prolonged exposure to livestock and foods such as non-sterilized breast milk and eggs. The results also suggest that babies can gain some protection against allergic diseases through breast milk, “says Järvinen-Seppo.

The Mennonites of the Old Order are Anabaptist Christians named after the Frisia reformer Minne Simens (1496-1561; commonly Dutchized to Menno Siemens) and a heritage of Switzerland and Southern Germany. I live in a traditional detached farm with few modern techniques. Their lifestyle is a rational substitute for the lifestyle of rural communities in Western countries until the dawn of the 20th century.

Järvinen-Seppo and colleagues found 52 mothers with babies 2 weeks to 6 months old in the old order Menonite community in Penn Yan, NY, and 29 with a modern urban lifestyle in the nearby city of Rochester. I collected breast milk from my mother. .. They used questionnaires and follow-up phone calls to ask mothers about their lifestyle and environment, and whether they or their babies had symptoms of atopic dermatitis. Next, we measured the milk concentration and activity of IgA antibodies, which are important for protecting the respiratory system and intestines from microorganisms, and the concentrations of fatty acid oligosaccharides, cytokines, and metabolites. They also used ribosomal RNA sequencing to determine which species of bacteria were milked from the mother to the baby.

As expected, old-order menonite mothers are exposed to farm animals, dogs, non-pasteurized farm milk, barns, high birth rates at home, and bleach to sterilize their homes. Self-reported that it is used frequently and exposed less. Antibiotics and pesticides. Importantly, they also reported a low incidence of atopic dermatitis in themselves and their babies.

Beneficial microorganisms and metabolites in human breast milk

Researchers have shown that breast milk from older Mennonite mothers is high in IgA1 and IgA2 antibodies against peanuts, egg white albumin, house dust mites, and bacteria. Streptococcus equii, Horse pathogen. Mennonite’s mother’s milk contained milk microbes such as bacteria from the Prevotellaceae, Veillonellaceae, and Micrococcaceae families, as well as high levels of certain oligosaccharides and fatty acids.

Dr. Anti E. Seppo, co-author of the University of Rochester Pediatrics, concludes: It “programs” the developing gut flora and the infant’s immune system. These may protect the baby from the development of allergic diseases. This is important because it helps explain why atopic dermatitis is currently exploding in the Western population. This is to prevent or alleviate these diseases. ”


Breastfeeding mothers do not transfer COVID through milk: study


For more information:
The traditional agricultural lifestyle of Old Older Mennonites regulates the composition of breast milk. Immunology Frontier (2021). DOI: 10.3389 / fimmu.2021.741513

Quote: Breast milk from Mennonite moms on the farm, allergies obtained on October 11, 2021 from https: //medicalxpress.com/news/2021-10-breast-mennonite-moms-farms-babies.html (2021) May 11) better protect your baby

This document is subject to copyright. No part may be reproduced without written permission, except for fair transactions for personal investigation or research purposes. The content is provided for informational purposes only.

Breast milk from Mennonite moms on farms may better protect babies from allergies Source link Breast milk from Mennonite moms on farms may better protect babies from allergies

The post Breast milk from Mennonite moms on farms may better protect babies from allergies appeared first on California News Times.

LEAVE A REPLY

Please enter your comment!
Please enter your name here

Share post:

Popular

More like this
Related

ETH 2.0 vision meets another roadblock but validators continue their march

Ethereum, the largest altcoin has continued to take measures...

Studies suggest that Americans are still suspicious of EVs

Plugin vehicles are popular in Europe, accounting for 21%...